Organoids

Organoids are 3D in vitro culture systems derived from self-organizing stem cells, recapitulating the in vivo architecture, functionality, and genetic signature of original tissues. Human tissue organoids have great potential in pharmaceutical research and testing, precision medicine and transplantation-based therapies. However, Earth -produced organoids require complex and sophisticated production processes with additives or supportive structures, making standardization and constant quality difficult to achieve. We have solved these Earth-based problems by producing in space: We developed a fully scalable biotechnological process to produce such human organoids from autologous mesenchymal stems in microgravity, where 3D growth and differentiation into complex tissues is achieved in the force-free environment.